![]() ![]() Gamma-chain is a common subunit shared by several cytokine receptors. The most frequent form of SCID, X-linked SCID (SCID-X1), is caused by mutations in the gamma-chain-encoding gene. SCIDs with lack of circulating T cells but a normal number of B cells accounts for 30 to 50% of all cases of human SCIDs. Typically, patients with SCID have a severe defect in T-cell differentiation, along with direct or indirect impairment of B-cell development and function. The sleep area includes unsafe items, such as pillows or blankets.īy following safe sleep recommendations, parents and caregivers can reduce the risk of SIDS and other sleep-related infant deaths.Severe combined immunodeficiency (SCID) comprises a heterogeneous group of monogenic disorders that result in early-onset severe infections by a range of pathogens (such as bacteria, viruses and fungi).Baby was born preterm (before 37 weeks) or at a low birth weight.The adult is a caregiver other than the baby’s parent, such as a grandparent or sibling.Baby is younger than 4 months old (regardless of adult smoking or sleep surface).The adult smokes cigarettes or uses tobacco products (even if they do not smoke in the bed).The adult is very tired, taking medication that makes them drowsy, or using substances like alcohol, or their ability to respond is affected in some way.The sleep surface is soft, such as a waterbed, old adult mattress, couch, or armchair.Bed sharing/sharing a sleep surface: Sharing an adult bed, couch, or armchair with baby can be especially dangerous in some situations:.Babies who share a room, but not a bed, with parents are at lower risk for SIDS and other sleep-related deaths than babies who sleep in their own room.Babies who sleep on an adult bed, couch, or armchair alone, with an adult, with a sibling, or with a pet are at very high risk for SIDS and sleep-related deaths from entrapment, suffocation, and strangulation.Pacifiers during sleep: Babies who sleep with pacifiers are at lower risk for SIDS than babies who do not use pacifiers during sleep.Illness*: Infants who have had a febrile illness, one with a high fever, within the past 2 to 3 weeks are at higher risk for SIDS.Immunizations: Vaccinated babies are at lower risk for SIDS than unvaccinated babies.Feeding human milk for some time is more protective against SIDS than not feeding human milk at all.Babies who are fed breastmilk are at lower risk for SIDS than formula-fed babies.Babies are more likely to overheat when they are placed on their stomachs to sleep.Overbundling, or dressing baby in too many layers of clothing and bedding for the temperature of the room, can increase the risk of SIDS,.Babies who get overheated are at higher risk for SIDS.Having items, such as blankets, bumpers, and stuffed toys, in the sleep area increases the risk for SIDS and other sleep-related deaths from suffocation, entrapment/wedging, and strangulation.Babies who sleep on a soft/squishy surface or under soft/fluffy bedding are at higher risk for SIDS and other sleep-related deaths from suffocation, entrapment/wedging, and strangulation.Black/African American and American Indian/Alaska Native babies are at higher risk for SIDS than are White, Hispanic, and Asian/Pacific Islander babies. Race/ethnicity*: Some racial/ethnic groups are at higher risk for SIDS than others.Drug and alcohol use during pregnancy increases baby’s risk for SIDS.Smoking during pregnancy greatly increases baby’s risk for SIDS. ![]() ![]() Getting regular medical care beginning early in and continuing throughout pregnancy reduces the risk of SIDS.Low birthweight babies, weighing 5 pounds, 8 ounces or less, are at higher risk for SIDS.Babies born early (before 37 weeks of pregnancy) are at higher risk for SIDS.Babies who are used to sleeping on their backs but who are placed on their stomachs or sides for sleep, like for a nap, are at very high risk of SIDS.Babies placed to sleep on their stomachs or sides are at higher risk for SIDS.Unchangeable factors appear with an asterisk (*) in the following list: Some are changeable, meaning parents and caregivers can take action to lower the risk. Research shows that certain factors and situations increase the risk for Sudden Infant Death Syndrome (SIDS) and other sleep-related infant deaths, such as from suffocation. ![]()
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